Biological signatures in clumped isotopes of O2

Statistical clumped isotope signatures

High precision measurements of molecules containing more than one heavy isotope may provide novel constraints on element cycles in nature. These so-called clumped isotope signatures are reported relative to the random (stochastic) distribution of heavy isotopes over all available isotopocules of a molecule, which is the conventional reference. When multiple indistinguishable atoms of the same e...

Biological hazards in toxicity of radioactive isotopes.

Dolomitization processes in hydrocarbon reservoirs: insight from geothermometry using clumped isotopes

Clumped isotopes geothermometry was applied to two dolomitic hydrocarbon reservoirs. Results indicate that late burial dolomitization occurred at ~110°C in the Albian Pinda dolostone (offshore Angola) and ~90°C in the Mano-Meillon dolostone (Aquitaine Basin, France), and did not continue on during subsequent burial/thermal evolution to present-day conditions (150160°C). This study illustrates t...

Constraints on the formation and diagenesis of phosphorites using carbonate clumped isotopes

Biological Convergence of Cancer Signatures

Gene expression profiling has identified cancer prognostic and predictive signatures with superior performance to conventional histopathological or clinical parameters. Consequently, signatures are being incorporated into clinical practice and will soon influence everyday decisions in oncology. However, the slight overlap in the gene identity between signatures for the same cancer type or condi...